Respiratory syncytial virus: from pathogenesis to potential …
WEBSep 27, 2021 · First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.
Structural landscape of the respiratory syncytial virus ... - Nature
WEBSep 15, 2023 · Human Respiratory Syncytial Virus (HRSV) is a prevalent cause of severe respiratory infections in children and the elderly. The helical HRSV nucleocapsid is a template for the viral RNA...
Respiratory syncytial virus entry and how to block it
WEBFeb 5, 2019 · The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc...
The Morphology and Assembly of Respiratory Syncytial Virus …
WEBAug 20, 2018 · Recently, the three-dimensional (3D) structure of purified RSV particles has been elucidated, revealing three distinct morphological categories: spherical, asymmetric, and filamentous. However, the native 3D structure of RSV particles associated with or released from infected cells has yet to be investigated.
Respiratory Syncytial Virus: Virology, Reverse Genetics, and ...
WEBHuman respiratory syncytial virus (RSV) is an enveloped, nonsegmented negative-strand RNA virus of family Paramyxoviridae. RSV is the most complex member of the family in terms of the number of genes and proteins.
Cryo-EM structure of the nucleocapsid-like assembly of respiratory ...
WEBAug 22, 2023 · Respiratory syncytial virus (RSV) is a nonsegmented, negative strand RNA virus that has caused severe lower respiratory tract infections of high mortality rates in infants and the elderly,...
The Morphology and Assembly of Respiratory Syncytial Virus
WEBAug 20, 2018 · RSV is a pleomorphic enveloped RNA virus in the Pneumoviridae family. Recently, the three-dimensional (3D) structure of purified RSV particles has been elucidated, revealing three distinct morphological categories: spherical, asymmetric, and …
WEBFigure 1. The schematic diagram of the genome organization and RNA synthesis of RSV. The leader (Le, cyan) and trailer (Tr, gold) are at 30 and 50 ends of the genome. The genes N, P, M2, L (blue), NS1, NS2, M, SH, G, and F (gray) are flanked with gene start (GS, white) and gene end (GE, black).
Standardized Phylogenetic Classification of Human Respiratory …
WEBJun 21, 2024 · Figure 1. The structure and genome of human respiratory syncytial virus (HRSV). A) Schematic of the HRSV virion structure detailing the location of structural proteins. B) Schematic of the HRSV genome organization... In 2022, HRSV was designated as Orthopneumovirus hominis species within the Pneumoviridae family.
Cryo-EM structure of the respiratory syncytial virus RNA …
WEBJan 17, 2020 · Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P).