What is multiplex PCR? - Front Line Genomics
WEBJul 26, 2021 · Multiplex PCR is a technique whereby PCR is used to amplify several different DNA sequences simultaneously. It is a type of target enrichment approach. It was first described in 1988 as a method to detect deletion mutations in the dystrophin gene – the largest known human gene. The dystrophin complex connects the cytoskeleton of …
A brief history of Next Generation Sequencing (NGS)
WEBJul 26, 2021 · 2000: Lynx Therapeutics Company launched the first of the NGS technologies, called Massively parallel signature sequencing (MPSS). The company was later bought by Illumina. 2004: 454 Life Sciences marketed a new generation pyrosequencing technology, called the Roche GS20. It was the first NGS platform on the …
Long-read sequencing vs short-read sequencing
WEBJul 26, 2021 · Long-read sequencing. Long-read sequencing technologies are capable of reading longer lengths, between 5,000 and 30,000 base pairs. Therefore, they immediately address one of the main challenges faced by short-read sequencing. They sequence a single molecule, eliminating amplification bias, and generate a reasonable length to …
A guide to proteomics - Front Line Genomics
WEBAug 27, 2021 · A guide to proteomics. The term ‘proteomics’ was first coined in 1996 by Marc Wilkins, used to define the large-scale analysis of all the proteins in a cell, tissue or organism. The goal of proteomics was to obtain a more wholesome view of biology, as opposed to studying each protein individually. Proteomics has evolved over the past …
DNA Sequencing: How to Choose the Right Technology
WEBAug 6, 2021 · The global market for DNA sequencing is predicted to grow from $15.7 billion in 2021 to $37.7 billion by 2026. The rising prevalence of viral diseases, such as COVID-19, and the increasing cases of cancer globally are likely to drive genomic research and propel the industry at an even more rapid rate.
Homepage - Front Line Genomics
WEBRegistered Office: Ground Floor, Cromwell House, 15 Andover Road, Winchester, Hampshire, SO23 7BT, United Kingdom. Tel: +44 (0)208 191 8810 Email: info ...
Sample Preparation for NGS – A Comprehensive Guide
WEBAug 21, 2024 · Step #3: Amplification. This is an optional step, but it is usually required. It is dependent on the application of NGS and the sample size. Amplification becomes essential to obtain enough coverage for reliable sequencing for samples with small amounts of starting material.
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Snake venom-related enzyme underlies COVID-19 mortality
WEBAug 26, 2021 · A new study, published in The Journal of Clinical Investigation, has identified a snake venom-related enzyme that may be the key cause of COVID-19 related mortality.Their findings have revealed a brand-new target for potential therapeutic treatments. The role of lipid metabolism in COVID-19. Up to 80% of individuals infected …
About - Front Line Genomics
WEBAddress: Ground Floor, Cromwell House, 15 Andover Road, Winchester, Hampshire, SO23 7BT. Telephone: +44 (0)208 191 8810. Email: [email protected]. At Front Line Genomics our mission is to deliver the benefits of genomics to patients faster. Our social mission drives everything we do.
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