Neutrophils in Kawasaki disease are prone to developing neutrophil extracellular traps (or NETosis), a process of cell activation, and sometimes cell death, which leads to extrusion of inflammatory ...
ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer
The inhibition of ERK5 is a potential complementary strategy for countering FAK inhibitor resistance in patients with lung ...
Alveolar macrophages, residing on the lung’s inner surface, constitute 55% of pulmonary immune cells. They can polarize into two distinct phenotypes: the classically activated (M1) and the ...
such as epithelial cell growth factors, reduce ALI in animal models. Reactive oxygen species are enhanced in ALI and propagate inflammatory cascades and lung injury. Antioxidants can attenuate ALI ...
a randomized phase III trial of carboplatin- or cisplatin-pemetrexed-pembrolizumab versus carboplatin- or cisplatin-pemetrexed in 492 patients with stage IV nonsquamous non–small cell lung cancer ...
June 13, 2024 — The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been ... Lung Cancer Study Offers ...
Targeted therapies and immunotherapies have radically improved treatment for advanced non-small-cell lung cancer (NSCLC). Tyrosine kinase inhibitors targeting oncogenic driver mutations continue to ...
Researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne have discovered new cells that drive the aging process in the thymus that could unlock a way to restore ...
Clusters are classified by their corresponding cell type, where blue corresponds to cells of the coelomic epithelium, red to those in the mesenchyme and green to coelomocytes. Color intensity shows ...
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