Researchers have uncovered a mechanism that may trigger ALS’s earliest stages, identifying proteins that mislocalize, causing ...

POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.

Approximately 5,000 people in the U.S. develop amyotrophic lateral sclerosis (ALS) each year. On average, they survive for ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

Approximately 5,000 people in the U.S. develop amyotrophic lateral sclerosis (ALS) each year. On average, they survive for only two to five years after being diagnosed, according to the Centers for ...

It has been shown in rats that silibinin protects neonatal hepatocytes from cell damage ... increase membrane stability in the presence of xenobiotic damage; capacity to regulate nuclear ...

Importantly, these imported chloroplasts displayed activity for two further days, during which time their host cells grew at an accelerated rate. This indicates that photosynthesis was indeed ...

Figure 2: In this example, a piece of intestine is cut out (1), and brush-border epithelial cells are dissociated to use them for nuclear transfer (2). Compared to the great stability of ...